After removing all the soiled straw and newspaper, I give the floor a brush and a wipe, line it with fresh newspapers and straw. If I have any garlic skins or lavender flowers then I'll toss them in to help repel insects.
Then all the hen house sweepings of manure and hay go into an old salvaged steel rubbish bin and i cover it in water, leave it for a few weeks and hey presto! Great fertiliser which goes straight into the compost.
Plus the hens have a sweet smelling hutch.
There was also a good article in the Weekly Times on the hen health, including hutch design and cleanliness.